As a modern, world-class and research-oriented facility, Aevitas Fertility Clinic strives to find and implement solutions to assist you in your fertility journey. Therefor, Aevitas makes use of the following specialised technology: PGD/PGS, cryopreservation/freezing of gametes and embryos, as well as Laser Assisted Hatching
PGD refers to genetic profiling of embryos prior to implantation. PGD requires in vitro fertilisation (IVF) in order to obtain oocytes or embryos for evaluation. Aevitas Fertility Clinic, uses PGD to screen for a specific genetic disease. PGD’s main advantage is that it avoids selective pregnancy termination, as PGD ensures that the embryo transferred will be free of the disease under consideration.
PGS, further applies the technology from PGD to screen for missing or additional chromosomes, which is a potential cause of miscarriages or implantation failure. Through identifying embryos with chromosomal abnormality, only embryos with normal chromosomal appearance are transferred, increasing the chances of a successful pregnancy.
Cryopreservation involves the preservation and maintenance of tissues at very low temperatures. Cryopreservation therefore allows flexibility during in vitro fertility treatment as frozen tissue can be stored indefinitely.
The cryopreservation of human sperm is an established procedure that has resulted in thousands of births. The freezing of sperm is advantageous, as partner sperm or donor sperm can be frozen and preserved for therapeutic insemination at a later stage. Frozen sperm can also be of use during assisted reproductive technologies (ART) as a secondary option, if a fresh sample cannot be collected on demand or if sample quality is poor on the day eggs are available.
The cryopreservation of human eggs (ova) is of advantage to the patient with ovarian disease or other conditions that could limit future egg production. Furthermore, women might choose to preserve their fertility for their own personal reasons, such as not having found the right partner to start a family with. Egg freezing allows women to preserve their own eggs and allows donor eggs to be frozen and used by a recipient, at a time most convenient for the recipient.
The cryopreservation of embryos typically takes place during an IVF cycle, for use at a later stage. The frozen embryo can be used in the case of a failed IVF cycle or for a second pregnancy at a later stage. Embryo cryopreservation therefore prevents the patient having to go through another full IVF cycle unnecessarily.
Laser assisted hatching is usually offered to patients with a thick outer egg wall (‘Zona Pellucida‘), -patients who have experienced repeated implantation failure and also often offered to older patients. Assisted hatching is used to help the embryo hatch from its protective outer shell and promote implantation in the uterine wall after embryo transfer.